Parthenocissus (pron.: /ˌpɑrθɨnɵˈsɪsəs/), is a genus of tendril climbing plants in the grape family, Vitaceae. It contains about 12 species native to the Himalayas, eastern Asia and North America. Several are grown for ornamental use, notably P. henryana, P. quinquefolia and P. tricuspidata.

The name derives from the Greek parthenos, "virgin", and kissos (Latinized as "cissus"), "ivy". The reason is variously given as the ability of these creepers to form seeds without pollination or the English name of P. quinquefolia, Virginia creeper, which has become attached to the whole genus.

Parthenocissus species are used as food plants by the larvae of some Lepidoptera species including Brown-tail and The Gothic.